There’ll be 800 patients in France, in which clinical trials have been launched last weekend.
“The listing of those potential drugs can also be depending on the record of experimental remedies classified as a priority from the World Health Organization,” said infectious diseases pro Florence Ader in tropical and infectious diseases division of Lyon’s Croix-Rousse hospital.
Ader is directing the French section of the trials that she states will be elastic meaning that”unsuccessful experimental therapies could be abandoned and replaced by [other people ] that originate from the study.”
Numerous studies beginning of antimalarial medication
The clinical drugs incorporate an evaluation of hydroxychloroquine, a medication that’s been discussed by many media organizations because of its possible efficacy in healing COVID-19.
“I’ve resisted many clinical trials in France including an evaluation of chloroquine for countless ill patients that are hospitalized.
The medication was used to deal with 24 individuals in Marseille using COVID-19 in a university hospital and also the preliminary results of the trial were published on March 20 at the International Journal of Antimicrobial Agents.
The analysis concluded that despite the small sample size, the treatment using a kind of chloroquine (hydroxychloroquine) and an antibiotic revealed a”reduction/disappearance” of this virus in several patients.
“Following six days, there was a considerable difference between individuals who had been treated vs not-treated,” said infectious disease specialist Didier Raoult who conducts the institute at Marseille in which the little trial had been completed. He explained 75 percent of those patients got better with this treatment.
He explained that some patients also showed considerable improvement within two days. The college hospital now says it’s going to deal with most patients it receives together with the medication treatment.
But many experts have stated it’s too early to tell whether the medication is successful.
“This isn’t the very first outbreak of a virus in which we’ve [an indication of] expect about a remedy and it ends up that it [did not work out] whatsoever. Hope is sufficient for me now to do everything that we could confirm whether it works or not,” said France’s health minister Véran.
“There is currently no treatment that’s been demonstrated to work against COVID-19,” WHO director-general Dr. Tedros Adhanom Ghebreyesus stated, while commending the power put into clinical therapies.
“Using untested drugs without the ideal signs could raise false hope,” he continued, saying that it might result in a lack of medication required for different ailments.
Françoise Barré-Sinoussi, that won the Nobel prize for her contribution to finding HIV, told Le Monde that serious study on the topic was needed and there were lots of continuing flaws from the Marseille research.
She added that she had been awaiting the outcomes of the clinical trials beginning in Europe that are being performed given clinical research”regulations”.
“nobody in the health care world is stating that Professor Raoult is incorrect to believe chloroquine may be an effective remedy against the coronavirus, but medication is not practiced through books [in the press ], it is not practiced according to a trial of 24 patients,” explained Michel Cymes, a head and neck surgeon and French clinical commentator in an interview with RTL.
The French investigators state the demand for remedies is urgent.
“There’s an urgent requirement for an effective remedy to treat symptomatic patients but also to lower the term of virus carriage to restrict the transmission locally,” the physicians in Marseille wrote.
However, US President Donald Trump recently came under criticism for saying that the medication was powerful and must be accepted in the USA.
Truly the medication had previously been analyzed in labs in China and is now the subject of a randomized University of Minnesota research with 1,500 participants to discover if it’s effective.
However, most say more study on the topic is necessary.