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Coronavirus: What’s Kawasaki disease and its potential link with COVID-19 in kids?

A mysterious illness affecting children that may be connected to COVID-19 was reported in many European nations and North America.

England’s healthcare had alarmed in the end of April which instances of children in intensive care of”a multi-system inflammatory condition” were climbing .

The UK, France, Italy, Spain, and the US have reported instances with a few kids testing positive for COVID-19 or even coronavirus radicals, which means they had been formerly exposed to the virus.

A nine-year-old in France lately died because of complications in cardiac arrest.

What are the symptoms to be aware of?
The WHO claims to be on the lookout for inflammation, fever, hypotension, and shock and New York City’s department of health cautioned to search for indications of fever, prolonged abdominal pain, skin rash, and bloodshot eyes, rushing heart amongst other symptoms.

The symptoms mentioned are very similar to Kawasaki Disease, which mostly affects children below the age of five and also may lead to blood vessels to become inflamed and swollen and result in complications like the swelling of the blood vessels.

“The features of this are fever, red eyes, red lips, red tongue, and a rash, and there may be redness and swelling of the palms and toes and there may also be swelling of the lymph nodes and throat,” said Adriana Treboulet, associate manager of the Kawasaki Disease Research Centre in the University of California, San Diego.

The disease may be mild but roughly a quarter of kids will probably have coronary artery aneurysms or swelling of their heart arteries, experts say.

“So Kawasaki disease was recognised for quite a while and it truly is as dreadful as it seems,” Kate Sullivan, a professor of paediatrics at The Children’s Hospital of Philadelphia. “There is inflammation of each organ of the human body.

“Normally what people see is your epidermis but what we’re afraid about is it impacts the heart and an inflammation of the heart is obviously harmful.”

What’s the documented connection between these signs and COVID-19?
In nations with substantial outbreaks of coronavirus, there are reported cases of paediatric jolt and Kawasaki disease-like symptoms. A number of those kids have tested positive for COVID-19 or even coronavirus antibodies.

France’s public health bureau stated they’ve had reports of 144 children with irregular paediatric ailments since March 1.

Some kids between the ages of 5 and 20 have introduced Kawasaki Disease like symptoms which the agency was calling”pseudo Kawasaki Disease”.

NHS England first warned in April that some kids have revealed symptoms of toxic shock syndrome — that is brought on by a bacteria getting into the human body and releasing harmful toxins — and also atypical Kawasaki disease”with blood parameters consistent with acute COVID-19 in kids”.

Spain’s paediatric institution set a similar warning in April, saying that there were instances of paediatric jolt but telling parents to not be alarmed.

“Examples of shock in children which are temporarily coinciding with the COVID-19 outbreak are extremely uncommon,” the institution clarified.

Experts say it’s too early to ascertain whether there is an immediate connection between the virus which leads to COVID-19 (SARS-CoV-2) and Kawasaki disease.

How can it be connected to COVID-19 and when will people know?
“First hypotheses are that this syndrome could be linked to COVID-19 according to first lab testing,” the WHO said on Friday.

The ancient NHS warning implied that”there could be yet another, as yet unknown, infectious pathogen related to these instances.”

Professor Robert Tulloh, a cardiologist in Bristol Royal Hospital for Children, advised Euronews last month:”There could be worse instances of [Kawasaki disease] since they’re introducing late – because they had been wrongly considered to be COVID-19 until too late. Or there could even be cases of Kawasaki disease triggered by COVID-19, masquerading as COVID-19 or even COVID-19-related.”

“​It takes several weeks prior to the epidemiologists can tell us whether there’s a hyperlink. It’ll be complex rather than an easy response,” Tulloh added.

Tulloh says there has been regarded as a connection between Kawasaki disease and SARS (Severe Acute Respiratory Syndrome) during the 2003 epidemic, but that concept has been disproven.

“Like COVID-19, Kawasaki disease may be moderate normally and we wouldn’t need to cause alarm or anxiety among parents of young kids,” additional Tulloh.

“But about a quarter of children with Kawasaki disease will acquire coronary artery aneurysms (swelling of the heart arteries) when they aren’t treated at the suitable time, which will be about 5 days to the illness.

Professor Russell Viner, President of the Royal College of Paediatrics and Child Health, worried that cases of kids falling badly ill with COVID-19 happen to be”quite rare”.

“Proof from across the world shows us that kids seem to be a part of the populace least influenced by this disease”

What exactly does the WHO state?
WHO affirmed in late April that it was exploring the rare inflammatory illness.

“They [kids ] often possess overwhelming moderate disease,” explained Dr Maria Van Kerkhove, COVID-19 technical guide at WHO’s health disasters programme.

“However, there are a number of kids who have developed acute disease and a few kids who’ve died.

“There are a few current uncommon descriptions of kids in certain European countries which have experienced this inflammatory syndrome, which can be very similar to Kawasaki’s syndrome”

The WHO requested for clinicians to be alert to the potential and ever since that time, more instances of this illness have been reported in many nations.